Graves disease is an auto-immune disorder in which there is the formation of antibodies called TSIs (Thyroid-stimulating antibodies) against receptors on the thyroid gland. These antibodies stimulate the thyroid gland to produce and secrete thyroid hormones which lead to increased levels of thyroid hormones in the blood. Thyroid hormones are very important in regulating various functions of the body so increased levels can cause various disturbances in functions of the body.
Graves disease has very characteristics symptoms which makes the diagnosis very obvious
Graves disease is diagnosed clinically based on signs and symptoms as it has very characteristic signs and symptoms, and by measuring the levels of TSH (Thyroid-stimulating hormone) and thyroid hormones T3 and T4. Both T3 and T4 levels are raised and TSH levels are reduced in Graves disease. Family history and medical history are important for the diagnosis as Graves disease may have a genetic predisposition. Radioactive Iodine uptake by the thyroid gland is increased in case of Graves disease. Ultrasound is done in pregnant patients who can not undergo the Radioactive Iodine Uptake test.
There is increased production of thyroid hormone in Graves disease so treatment is mainly based on lowering the levels of thyroid hormones in the body. Some commonly used treatment options are available which your doctor opts for you based on your health status and history of other diseases.
RADIOACTIVE IODINE UPTAKE
SURGICAL REMOVAL OF THE THYROID GLAND OR SOME OF ITS PORTION
Consult your doctor to help you out in choosing the best treatment option for you based on the health status and severity of your disease.
THYROID STORM- thyrotoxic crisis when hyperthyroidism is left untreated
BRITTLE BONES- as the body ability to incorporate calcium ions into bones is affected by the thyroid hormone.
HEART DISORDER- heart failure and irregular heart rhythms can happen due to increased blood thyroid hormones level.
In about 30 percent of patients of Graves disease, there is bulging of the eyeball due to swelling of tissues and muscles of orbits. It is one of the very common causes of proptosis in female patients characterized by
Graves disease is sometimes associated with the thickening and reddening of skin called Graves Dermopathy.